Kyntheum 210mg Opl Inj Voorgev.sp.2x1,5ml 140mg/ml

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Serious side effects

Stop using Kyntheum and tell your doctor or seek medical help immediately if you get any of the following side effects. Your doctor will decide if and when you may restart the treatment:

Serious allergic reaction (may affect up to 1 in 1,000 people), the signs may include: • difficulty breathing or swallowing • low blood pressure, which can cause dizziness or light-headedness • swelling of the face, lips, tongue or throat • severe itching of the skin, with a red rash or raised bumps.

Possible serious infections (may affect up to 1 in 100 people), the signs may include: • fever, flu-like symptoms, night sweats • feeling tired or short of breath, cough which will not go away • warm, red and painful skin, or a painful skin rash with blisters.

Other side effects

Common (may affect up to 1 in 10 people) • diarrhoea • feeling sick • redness, pain, itching, bruising, or bleeding at injection site • tiredness • mouth or throat pain • tinea (fungal) skin infections (including on feet and groin) • flu (influenza) • headache • joint pain
• muscle pain.

Uncommon (may affect up to 1 in 100 people) • candida (fungal) infection in the mouth, throat or genitals • discharge from the eye with itching, redness and swelling (conjunctivitis) • low white blood cell count.

Most of these side effects are mild to moderate. If any of these side effects becomes severe, tell your doctor, nurse, or pharmacist.

Abdominal cramps and pain, diarrhoea, weight loss or blood in the stool (signs of bowel problems) have also been reported with IL-17 inhibitors, such as Kyntheum.

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects you can help provide more information on the safety of this medicine.